Detalhe da pesquisa
1.
Modified messenger-RNA components alter the encoded protein.
Nature
; 625(7993): 37-38, 2024 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-38093050
2.
Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1.
J Immunol
; 209(1): 118-127, 2022 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35750334
3.
Strategic Variants of CSP Delivered as SynDNA Vaccines Demonstrate Heterogeneity of Immunogenicity and Protection from Plasmodium Infection in a Murine Model.
Infect Immun
; 89(10): e0072820, 2021 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34152830
4.
Gene-encoded nanoparticle vaccine platforms for in vivo assembly of multimeric antigen to promote adaptive immunity.
Wiley Interdiscip Rev Nanomed Nanobiotechnol
; 15(4): e1880, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36807845
5.
Engineered antibody cytokine chimera synergizes with DNA-launched nanoparticle vaccines to potentiate melanoma suppression in vivo.
Front Immunol
; 14: 1072810, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36911698
6.
Adenosine deaminase augments SARS-CoV-2 specific cellular and humoral responses in aged mouse models of immunization and challenge.
Front Immunol
; 14: 1138609, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36999023
7.
Engineered DNA-encoded monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein confer single dose protection in a murine malaria challenge model.
Sci Rep
; 12(1): 14313, 2022 08 22.
Artigo
Inglês
| MEDLINE | ID: mdl-35995959
8.
In vivo DNA-launched bispecific T cell engager targeting IL-13Rα2 controls tumor growth in an animal model of glioblastoma multiforme.
Mol Ther Oncolytics
; 26: 289-301, 2022 Sep 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36090479
9.
Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo.
Cell Rep Med
; 3(7): 100693, 2022 07 19.
Artigo
Inglês
| MEDLINE | ID: mdl-35839767
10.
Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer.
Nat Commun
; 13(1): 695, 2022 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35121758
11.
DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2.
Nat Commun
; 13(1): 5886, 2022 10 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36202799
12.
Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection.
Cell Rep
; 38(5): 110318, 2022 02 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35090597
13.
Uropathogenic Escherichia coli Infection Compromises the Blood-Testis Barrier by Disturbing mTORC1-mTORC2 Balance.
Front Immunol
; 12: 582858, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33679734
14.
A novel mouse AAV6 hACE2 transduction model of wild-type SARS-CoV-2 infection studied using synDNA immunogens.
iScience
; 24(7): 102699, 2021 Jul 23.
Artigo
Inglês
| MEDLINE | ID: mdl-34124612
15.
Intradermal-delivered DNA vaccine induces durable immunity mediating a reduction in viral load in a rhesus macaque SARS-CoV-2 challenge model.
Cell Rep Med
; 2(10): 100420, 2021 10 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34604818
16.
Harnessing Recent Advances in Synthetic DNA and Electroporation Technologies for Rapid Vaccine Development Against COVID-19 and Other Emerging Infectious Diseases.
Front Med Technol
; 2: 571030, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-35047878
17.
A DNA-Launched Nanoparticle Vaccine Elicits CD8+ T-cell Immunity to Promote In Vivo Tumor Control.
Cancer Immunol Res
; 8(11): 1354-1364, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32913042
18.
Synthetic DNA Vaccines Adjuvanted with pIL-33 Drive Liver-Localized T Cells and Provide Protection from Plasmodium Challenge in a Mouse Model.
Vaccines (Basel)
; 8(1)2020 Jan 10.
Artigo
Inglês
| MEDLINE | ID: mdl-31936739